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2011

Weisbrodt L, McKinley S, Marshall AP, Cole L, Seppelt IM and
Delaney A. Daily Interruption of Sedation in Patients Receiving Mechanical Ventilation. Am J Crit Care, July 2011, Volume 20, No. 4.

Pettila V, Westbrook AJ, Nichol AD, Bailey MJ, Wood EM, Syres G, Phillips, LE, Street A, French C, Murray L, Orford N, Santamaria JD,
Bellomo R, Cooper DJ for the Blood Observational Study Investigators for the ANZICS Clinical Trials Group. Age of red blood cells and mortality in the critically ill. Critical Care 2011, 15:R116 (http://ccforum.com/content/15/2/R116)

Pettila V, Webb SA, Bailey M, Howe B, Seppelt IM, Bellomo R on behalf of the ANZIC Influenza Investigators and Australian New Zealand Intensive Care Society Clinical Trials Group. Acute kidney injury in patients with influenza A (H1N1) 2009. Intensive Care Med 2011; 37: p. 763-7.

Cooper DJ, Rosenfeld JV, Murray L, Arabi YM, Davies AR, D'Urso P, Kossmann T, Ponsford J, Seppelt I, Reilly P and Wolfe R for the DECRA Trial Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Decompressive Craniectomy in Diffuse Traumatic Brain Injury. N Engl J Med, 2011. 364(16): p. 1493-502.

The Crystalloid versus Hydroxyethyl Starch Trial (CHEST) Management Committee The Crystalloid versus Hydroxyethyl Starch Trial: protocol for a multi-centre randomised controlled trial of fluid resuscitation with 6% hydroxyethyl starch (130/0.4) compared to 0.9% sodium chloride (saline) in intensive care patients on mortality. Intensive Care Med, Volume 37 (5), May 2011, p. 816-823.

Cook D, Meade M, Guyatt G, Walter SD, Heels-Ansdell D, Geerts W, Warkentin TE, Cooper DJ, Zytaruk N, Vallance S, Berwanger O, Rocha M, Qushmaq I, Crowther M. PROphylaxis for ThromboEmbolism in Critical Care Trial protocol and analysis plan. J Crit Care. 2011 Apr;26(2):223.e1-9.

The PROTECT Investigators for the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Dalteparin versus Unfractionated Heparin in Critically Ill Patients. N Engl J Med, March 22, 2011.

Yung M, Slater A, Festa M, Williams G, Erickson S, Pettila V,
Alexander J, Howe B and Shekerdemian L; Australia and New Zealand Intensive Care Influenza Investigators and the Paediatric Study Group and the Clinical Trials Group of the Australia New Zealand Intensive Care Society. Pandemic H1N1 in children requiring intensive care in Australia and New Zealand during winter 2009. Pediatrics 2011; 127:e156-63.

Davies A, Morrison S, Ridley E, Bailey M, Banks M, Cooper DJ, Hardy  G, McIlroy K and Thomson A for the ASAP Study Investigators. Nutritional therapy in patients with acute pancreatitis requiring critical care unit management: A prospective observational study in Australia and New Zealand. Crit Care Med 2011; 39:462-8.

The SAFE Study Investigators. Impact of albumin compared to saline on organ function and mortality of patients with severe sepsis. Intensive Care Med 2011; 37:86-96

2010

Finfer S, Liu B, Taylor C, Bellomo R, Billot L, Cook D, Du B, McArthur C and Myburgh J for the SAFE TRIPS Investigators. Resuscitation fluid use in critically ill adults: an international cross-sectional study in 391 intensive care units. Critical Care; 15 October 2010; 14:R185. http://ccforum.com/content/14/5/R185

Knight M, Pierce M, Seppelt I, Kurinczuk JJ, Spark P, Brocklehurst P, McLintock C, Sullivan E on behalf of the UK’s Obstetric Surveillance System, the ANZIC Influenza Investigators, and the Australasian Maternity Outcomes Surveillance System. Critical illness with AH1N1v influenza in pregnancy: a comparison of two population-based cohorts. BJOG; 13 Oct 2010; Online.

The Blood Observational Study Investigators on behalf of the ANZICS-Clinical Trials Group. Transfusion practice and guidelines in Australian and New Zealand intensive care units. Intensive Care Med; May 2010; Online.

Chen J, Bellomo R, Hillman K, Flabouris A, Finfer S and the MERIT Study Investigators for the Simpson Centre and the ANZICS Clinical Trials Group. Triggers for emergency team activation: A multicenter assessment. J Crit Care; Epub March 1 2010.

Robertson MS, Nichol AD, Higgins AM, Bailey MJ, Presneill JJ, Cooper DJ, Webb SA, McArthur C, MacIsaac CM and the VTE Point Prevalence Investigators for the Australian and New Zealand Intensive Care Research Centre (ANZIC-RC) and the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG). Venous thromboembolism prophylaxis in the critically ill: a point prevalence survey of current practice in Australian and New Zealand intensive care units. Criti Care Resusc; March 2010; 12(1): 9-15

Flabouris A, Chen J, Hillman K, Bellomo R, Finfer S and The MERIT Study Investigators from the Simpson Centre and the ANZICs Clinical Trials Group. Timing and interventions of emergency teams during the MERIT study. Resuscitation; January 2010; 81(1): 25-30.

Bellomo R, Pettilä V, Webb SAR, Bailey M, Howe B and Seppelt IM. Acute Kidney Injury and 2009 H1N1 Influenza-Related Critical Illness. Contrib Nephrol; 2010; 165:310-14.

The ANZIC Influenza Investigators and Australasian Maternity Outcomes Surveillance System. Critical illness due to 2009 A/H1N1 influenza in pregnant and postpartum women: population based cohort study. BMJ, 2010; 340:c1279.

2009

Bellomo R, Morimatsu H, Presneill J, French C, Cole L, Story D, Uchino S, Naka T, Finfer S, Cooper DJ and Myburgh J, on behalf of the SAFE Study Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Effects of saline or albumin resuscitation on standard coagulation tests. Crit Care Resusc, 2009; 11: 250-256.

Chen J, Flabouris A, Bellomo R, Hillman K, Finfer S, MERIT investigators for the Simpson Centre and the ANZICS Clinical Trial Group. Baseline hospital performance and the impact of medical emergency teams: Modelling vs. conventional subgroup analysis. Trials; December 2009; 10:117.

The ANZIC Influenza Investigators. Critical care services and 2009 H1N1 influenza in Australia and New Zealand. N Engl J Med, November 2009; 361(20):1925-34.

The RENAL Replacement Therapy Study Investigators. Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients. N Engl J Med. October 2009; 361(17):1627-38.

Webb SAR and Seppelt IM for the ANZIC Influenza Investigators. Pandemic (H1N1) 2009 influenza (“swine flu”) in Australian and New Zealand intensive care. Crit Care Resusc. September 2009; 11(3):170-172

NICE-SUGAR Study Investigators, Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Henderson WR, Hébert PC, Heritier S, Heyland DK, McArthur C, McDonald E, Mitchell I, Myburgh JA, Norton R, Potter J, Robinson BG, Ronco JJ. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. Mar 26 2009; 360(13):1283-97. Epub 2009 Mar 24.

Finfer S, Heritier S; NICE Study Management Committee and SUGAR Study Executive Committee. The NICE-SUGAR (Normoglycaemia in Intensive Care Evaluation and Survival Using Glucose Algorithm Regulation) Study: statistical analysis plan. Crit Care Resusc. March 2009; 11(1): 46-57.

Chen J, Hillman K, Bellomo R, Flabouris A, Finfer S, Cretikos M; MERIT Study Investigators for the Simpson Centre; ANZICS Clinical Trials Group. The impact of introducing medical emergency team system on the documentations of vital signs. Resuscitation. Jan 2009; 80(1): 35-43. Epub 2008 Nov 17.

Chen J, Bellomo R, Flabouris A, Hillman K , Finfer S; MERIT Study Investigators for the Simpson Centre; ANZICS Clinical Trials Group. The relationship between early emergency team calls and serious adverse events. Crit Care Med. Jan 2009; 37(1):148-53.

Nichol AD, Cooper DJ, POLAR Study Investigators on behalf of the ANZICS-Clinical Trials Group, EPO Study Investigators on behalf of the ANZICS-Clinical Trials Group. Can we improve neurological outcomes in severe traumatic brain injury? Something old (early prophylactic hypothermia) and something new (erythropoietin). Injury. May 2009; 40(5): 471-8. Epub 2009 Apr 15.

Peake SL, Bailey M, Bellomo R, Cameron PA, Cross A, Delaney A, Finfer S, Higgins A, Jones DA, Myburgh JA, Syres GA, Webb SA, Williams P, ARISE Investigators for the Australian and New Zealand Intensive Care Society Clinical Trials Group. Australasian resuscitation of sepsis evaluation (ARISE): A multi-centre, prospective, inception cohort study. Resuscitation. Jul 2009; 80(7): 811-8. Epub 2009 May 20.

The RENAL Investigators. The Randomized Evaluation of Normal vs. Augmented Level Replacement Therapy (RENAL) Trial: A statistical analysis plan. Crit Care Resusc. 2009; 11:59-66

2008

Chen J, Flabouris A, Bellomo R, Hillman K, Finfer S, MERIT Study Investigators for the Simpson Centre and the ANZICS Clinical Trials Group. Medical Emergency Team System and not-for-resuscitation orders: results from the MERIT study. Resuscitation. Dec 2008; 79(3): 391-7. Epub 2008 Oct 25.

Doig GS, Simpson F, Finfer S, Delaney A, Davies AR, Mitchell I, Dobb G, Nutrition Guidelines Investigators of the ANZICS Clinical Trials Group. Effect of evidence-based feeding guidelines on mortality of critically ill adults: a cluster randomized controlled trial. JAMA. Dec 17 2008; 300(23): 2731-41

The RENAL Study Investigators. Screening and Study Enrolment in the Randomized Evaluation of Normal vs. Augmented Level (RENAL) Replacement Therapy Trial. Blood Purif. 2008; 27: 199-205

The RENAL Study Investigators. Design and Challenges of the Randomized Evaluation of Normal vs. Augmented Level Replacement Therapy (RENAL) Trial: High Dose vs. Standard Dose Hemofiltration in Acute Renal Failure. Blood Purif. 2008;26:407-416

The RENAL Study Investigators. Real replacement therapy for acute kidney injury in Australia and New Zealand intensive care units: a practice survey. Crit Care Resusc. 2008; 10: 225-230

Yung M, Wilkins B, Norton L, Slater A and the Paediatric Study Group of the Australian and New Zealand Intensive Care Society. Glucose control, organ failure and mortality in pediatric intensive care. Pediatr Crit Care Med. 2008; 9(2): 147-52

Cook DJ, Blythe D, Rischbieth A, Hebert PC, Zytaruk N, Menon K, Erikson S, Fowler R, Heels-Ansdell D, Meade MO for the Canadian Critical Care Trials Group and the ANZICS Clinical Trials Group. Enrolment of ICU Patients into Clinical Studies: A Tri-national Survey. Crit Care Med. Jul 2008; 36(7):2100-5

Dulhunty JM, Lipman J, Finfer S and the Sepsis Study Investigators for the ANZICS Clinical Trials Group. Does severe non-infectious SIRS differ from severe sepsis? Results from a multi-centre Australian and New Zealand intensive care unit study. Intens Care Med. 2008; 34(9):1654-1661.

Myburgh JA, Cooper DJ, Finfer SR, Venkatesh B, Jones D, Higgins A, Bishop N, Higlett T and the Australasian Traumatic Brain Injury Study (ATBIS) Investigators for the ANZICS Clinical Trials Group. Epidemiology and 12-month outcomes from traumatic brain injury in Australia and New Zealand. J Trauma. 2008; 64(4):854–62.

Moran J, Bersten A, Solomon P, Edibam C, Hunt T and the ANZICS Clinical Trials Group. Modelling survival in acute severe illness: Cox versus accelerated failure time models. J Eval Clin Pract. 2008; 14:83-93.

Hicks P and Cooper DJ, Webb SAR, Myburgh JA, Seppelt IM, Peake SL, Joyce C, Stephens DP, Turner A, French C, Hart G, Jenkins IR, Burrell AR on behalf of the ANZICS Board and the ANZICS Clinical Trials Group Executive Committee. The Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. An assessment by the Australian and New Zealand Intensive Care Society. Anaesth Intensive Care. 2008; 36(2):149-51.

Hicks P, Cooper DJ, Webb SAR, Myburgh JA, Seppelt IM, Peake SL, Joyce C, Stephens DP, Turner A, French C, Hart G, Jenkins IR, Burrell AR on behalf of the ANZICS Board and the ANZICS Clinical Trials Group Executive Committee. The Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. An assessment by the Australian and New Zealand Intensive Care Society. Crit Care Resusc. 2008; 10:8.

2007

Cretikos MA, Chen J, Hillman KM, Bellomo R, Finfer SR, Flabouris A and The MERIT Study Investigators. The effectiveness of implementation of the medical emergency team (MET) system and factors associated with use during the MERIT study. Crit Care Resusc. 2007; 9(2):206-12.

Cretikos M, Chen J, Hillman K, Bellomo R, Finfer S, Flabouris A and The MERIT Study Investigators. The objective medical emergency team activation criteria: A case-control study. Resuscitation. 2007; 73(1):62-72.

Erickson S, Schibler A, Numa A, Nuthall G, Yung M, Pascoe E, Wilkins B on behalf of the Paediatric Study Group; Australian and New Zealand Intensive Care Society. Acute lung injury in pediatric intensive care in Australia and New Zealand- A prospective, multicenter, observational study. Ped Crit Care Med. 2007; 8(4):317-23.

Jones DA, Cooper DJ, Finfer SR, Bellomo R, Myburgh JA, Higgins A, Peake SL, Jenkins I and McNeil J. Advancing Intensive Care Research in Australia and New Zealand – development of the bi-national ANZIC Research Centre. Crit Care Resusc. 2007; 9(2):198-204.

Myburgh JA, Finfer SR and Bellomo R. The Australian and New Zealand Intensive Care Society Clinical Trials Group. ICU Management. 2007; 7:43-45.

Myburgh JA and Skowronski G. The maturation of academic Intensive Care Medicine in Australia and New Zealand: time to capitalise on progress. Anaesth Intensive Care. 2007, 35:169-170.

The Australasian Resuscitation in Sepsis Evaluation (ARISE) Investigators and the Australian and New Zealand Intensive Care Society (ANZICS) Adult Patient Database (APD) Management Committee. The outcome of sepsis and septic shock presenting to the emergency department in Australia and New Zealand. Crit Care Resusc. 2007; 9(1):8-18.

The SAFE Study Investigators. Saline or albumin for fluid resuscitation in patients with traumatic brain injury. N Engl J Med. 2007; 357(9):874-84.

2006

Bellomo R, Morimatsu H, French C, Cole, L, Story, D, Uchino, S, Naka, T on behalf of the SAFE study investigators. The effects of saline or albumin resuscitation on acid-base status and serum electrolytes. Crit Care Med. 2006; 34(12):2891-2897.

The SAFE Study Investigators. Effect of baseline serum albumin concentration on outcome of resuscitation with albumin or saline in patients in Intensive Care Units: Analysis of data from the Saline versus Albumin Fluid Evaluation (SAFE) Study. BMJ. 2006; 333(7577):1044-1049.

Finfer S, Felton T, Blundell A, Lipman J and the ANZICS Clinical Trials Group Sepsis Investigators. Estimate of the number of patients eligible for treatment with drotrecogin alfa (activated) based on differing international indications: Post-hoc analysis of an inception cohort study in Australia and New Zealand. Anaesth Intensive Care. 2006; 34(2):184-190.

Mitchell I, Finfer S, Bellomo R, Higlett T and the ANZICS Clinical Trials Group Glucose Management Investigators. Management of blood glucose in the critically ill in Australia and New Zealand: A practice survey and inception cohort study. Intensive Care Med. 2006; 32(6):867-74.

Mitchell I, Knight E, Gissane J, Tamhane R, Kolli R, Leditschke A, Bellomo R, Finfer S and the Australia and New Zealand Intensive Care Society Clinical Trials Group. A Phase II Randomised Controlled Trial of Intensive Insulin Therapy in General Intensive Care Patients. Crit Care Resusc. 2006; 8(4):289-93.

2005

The NICE – SUGAR Study Investigators. The Normoglycemia in Intensive Care Evaluation (NICE) (ISRCTN04968275) and Survival Using Glucose Algorithm Regulation (SUGAR) Study: Development, design and conduct of an international multi-center, open label, randomized controlled trial of two target ranges for glycemic control in intensive care unit patients. Am J Respir Crit Care Med. 2005:172; (C) http://ajrccm.atsjournals.org/cgi/data/172/11/1358/DC1/1

Rischbieth A, Blythe D and the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG). Ethical intensive care research: development of an ethics handbook. Crit Care Resusc. 2005; 7(4):310-21.

MERIT study investigators. Introduction of the medical emergency team (MET) system: a cluster-randomised controlled trial. Lancet. 2005; 365:2091-97.

Cook DJ, Rocker G, Meade M, Guyatt G, Geerts W, Anderson D, Skrobik Y, Hebert P, Albert M, Cooper DJ, Bates S, Caco C, Finfer S, Fowler S, Freitag A, Granton J, Jones G, Langevin S, Mehta S, Pagliarello G, Poirier G, Rabbat C, Schiff D, Griffith L, Crowther M for the PROTECT investigators and the Canadian Critical Care Trials Group. Prophylaxis for ThromboEmbolism in Critical Care (PROTECT) Trial: A Pilot Study. J Crit Care. 2005; 20(4):364-372.

Cooper DJ, Bishop N, Cade J, Finfer S, Gallus A, Myburgh J for the Australian and New Zealand Intensive Care Society Clinical Trials Group. Thromboprophylaxis for intensive care patients in Australia and New Zealand: A brief survey report. J Crit Care. 2005; 20(4):354-6.

Boots R, Lipman J, Bellomo R, Stephens D, Heller RF, for the ANZICS-CTG. The spectrum of practice in the diagnosis and management of pneumonia in patients requiring mechanical ventilation. Australian and New Zealand Practice in Intensive Care (ANZPIC II). Anaesth Intens Care. 2005; 33:87-100.

Boots R, Lipman J, Bellomo R, Stephens D, Heller RF, for the ANZICS-CTG. Disease risk and mortality prediction in intensive care patients with pneumonia. Australian and New Zealand Practice in Intensive Care (ANZPIC II). Anaesth Intensive Care. 2005; 33:101-111.

Boots R, Lipman J, Bellomo R, Stephens D, Heller RF, for the ANZICS-CTG. Predictors of physician confidence to diagnose pneumonia and determine illness severity in ventilated patients. Australian and New Zealand Practice in Intensive Care (ANZPIC II). Anaesth Intensive Care. 2005; 33:112-119.

2004

Finfer SR, Boyce NW, Norton RN. The SAFE Study: a landmark trial of the safety of albumin in intensive care. Med J Aust. 2004; 181:237-238.

The SAFE Study Investigators. A comparison of Albumin and Saline for Fluid Resuscitation in the Intensive Care Unit (The SAFE Study). N Engl J Med. 2004; 350:2247-2256.

Finfer S, Bellomo R, Lipman J, French C, Dobb G, Myburgh J and the ANZICS Clinical Trials Group Sepsis Investigators. Adult-population incidence of severe sepsis in Australian and New Zealand intensive care units. Intensive Care Med. 2004; 30:589-596.

Kause J, Smith G, Prytherch D, Parr M, Flabouris A, Hillman K for the Intensive Care Society (UK) & Australian and New Zealand Intensive Care Society Clinical Trials Group ACADEAMIA Investigators. A comparison of Antecedents to Cardiac Arrests, Deaths and EMergency Intensive care Admissions in Australia and New Zealand, and the United Kingdom—the ACADEMIA study. Resuscitation. 2004; 62:275-82.

2003

Finfer S, Bellomo R, Myburgh J, Norton R. Efficacy of albumin in critically ill patients: Large trial in Australia and New Zealand may provide an answer. BMJ. 2003; 326:559-560.

ANZICS Clinical Trials Group and Institute for International Health SAFE Study Investigators. The Saline vs. Albumin Fluid Evaluation (SAFE) Study (ISRCTN76588266): Design and conduct of a multi-centre, blinded randomised controlled trial of intravenous fluid resuscitation in critically ill patients. BMJ.com http://bmj.com/cgi/content/full/326/7389/559/DC1 (Accessed 17th March 2003) (C)

2002

French CJ, Bellomo R, Finfer SR, Lipman J, Chapman M, Boyce NW and the ANZICS Clinical Trials Group. Appropriateness of red blood cell transfusion in Australasian intensive Care practice. Med J Aust. 2002; 177:548-55.

Bersten AD, Edibam C, Hunt T, Moran J and the ANZICS CTG. Incidence and Mortality of acute lung injury (ALI) and the Acute Respiratory Distress Syndrome (ARDS) in three Australian states. Am J Respir Crit Care Med. 2002; 165:443-448.

2001

Finfer S, Myburgh J, Bellomo R. The ANZICS Clinical Trials Group 1994-2001: developing a unique research strategy. World Federation Journal of Critical Care. 2001; Congress Edition:14-17.

2000

Bellomo R, Chapman M, Finfer S, Hickling K, Myburgh J and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Low dose dopamine in patients with early renal dysfunction: a placebo controlled randomised trial. Lancet. 2000; 356:2139-2143.

1998

Bellomo R, Bersten AD, Boots RJ, Bristow PJ, Dobb GJ, Finfer SR, McArthur CJ, Richards B, Skowronski GA, The Australian and New Zealand Intensive Care Multicentre Studies Group Investigators. The use of antimicrobials in ten Australian and New Zealand intensive care units. Anaesth Intensive Care. 1998; 26:648-653.

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