​Clinical Trials Group 


CTG Current Research
You can select the short title below for more information on the study.

collapse Status : Set up phase ‎(8)
CTG 1516-04BLING IIIA phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients
CTG 1617-04LUCIDLiberal glucose control in critically Ill patient with pre-existing type 2 diabetes (LUCID): a phase II multicentre randomised controlled trial
CTG 1415-02OPTIMISE-CAP (CTG Supported Study)Optimisation by platform trial involving multiple interventions with simultaneous evaluation in community acquired pneumonia
CTG 1415-01PEPTICA multi-centre, cluster cross over, randomised registry trial comparing the safety and efficacy of proton pump inhibitors with histamine-2 receptor blockers for ulcer prophylaxis in intensive care patients
CTG 1415-03PLUSThe Plasma-Lyte 148® vs Saline study
CTG 1617-03REACTORRandomised evaluation of active control of temperature vs. ordinary temperature management (The REACTOR trial)
CTG 1314-13SuDDICU cRCT (CTG Supported Study)A cluster randomised controlled trial of the clinical effectiveness and cost-effectiveness with a contemporaneous study of the ecological impact of selective decontamination of the digestive tract in critically ill patients treated in intensive care units
CTG 1516-05TEAM RCTTreatment of invasively ventilated adults with Early Activity and Mobilisation
collapse Status : Currently recruiting ‎(16)
CTG 10-01ADRENALADjunctive corticosteroid tREatment iN criticAlly IlL patients with septic shock
CTG 1213-03ADRENAL Consent SubstudyA multi-centre, prospective, observational study of the process of obtaining consent from potential participants or their substitute decision-makers in the ADjunctive corticosteroid treatment iN criticAlly ilL patients with septic shock (ADRENAL) study
CTG 1314-09BabySPICE PilotSedation practice in paediatric intensive care in Australia and New Zealand
CTG 1415-04ICU-ROXA phase 2b, multi-centre, randomised, single blinded clinical trial parallel groups comparing liberal vs. conservative oxygen therapy in mechanically ventilated adults in the Intensive Care Unit (ICU)
CTG 1314-05PATCHPre-hospital anti-fibrinolytics for traumatic coagulopathy and haemorrhage
CTG 10-008PHARLAPA multicentre RCT of open lung strategy including permissive hypercapnia, alveolar recruitment and low airway pressures in patients with ARDS
CTG 1415-05PINBALL PilotProphylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: a pilot randomised controlled trial
CTG 08-002POLARProphylactic hypothermia to lessen traumatic brain injury
CTG 1213-05REACT Shock StudyRelative Hypotension and Acute Kidney Injury in Patients with Shock: A Prospective Multicentre Cohort Study
CTG 12-002RELIEFREstrictive versus LIbEral Fluid Therapy in Major Abdominal Surgery
CTG 1314-04SMARRTSampling antibiotics in renal replacement therapy
CTG 12-003SPICE RCTAustralian sedation practice in intensive care evaluation; randomised trial
CTG 1516‐01SPRINT‐SARIShort Period Incidence Study of Severe Acute Respiratory Infection
CTG 1516-02STARRT-AKI (CTG Supported Study)Standard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury
CTG 1314-08TARGET RCTThe augmented versus routine approach to giving energy trial
CTG 1516-03The BALANCE Study (CTG Supported Study)Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT
collapse Status : Analysis & reporting ‎(10)
CTG 1314-14 iPIT3 – The Influenza Pandemic SurveyA survey of Australian public opinion on methods to triage intensive care patients in an influenza pandemic
CTG 08-007ARISE Economic EvaluationEconomic Evaluation of Resuscitation in Sepsis
CTG 10-006BLISSBacteraemic load and survival in septic patient
CTG 12-006Delayed Discharge StudyEvaluation of clinical outcomes and cost consequences of delayed discharge from intensive care: A multicentre prospective observational study
CTG 1314-07EGDT IPDMAMulti-Centre randomised controlled trials of early goal-directed therapy (EGDT) in severe sepsis – an individual patient data meta-analysis (IPDMA)
CTG 1314-10Fluid-TRIPSThe Fluid Translation of Research into Practice Study (Fluid-TRIPS): An International Cross sectional Survey of Fluid Resuscitation Practice
CTG 1213-01PINBALL inception cohort studyProphylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: an inception cohort study
CTG 10-005POLAR BEARThe Prophylactic hypOthermia trial to Lessen traumatic bRain injury Basal Energy Assessment Research
CTG 11-005The RENAL Substudy of POLARThe RENAL Substudy of POLAR
CTG 10-010TRANSFUSEStandard issue transfusion versus fresher red blood cell use in intensive care - a randomised controlled trial