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INTUBE

ANZICS CTG Supported Study

INTUBE

International Observational Study to Understand the Impact and Best Practices of Airway Management in Critically Ill Patients

Study Description

Endotracheal intubation (ETI) in critically ill patients is a potentially life-threatening procedure and approximately one-third of ETIs is complicated by severe hypoxia, cardiovascular collapse and cardiac arrest. Critically ill are prone to severe complications as the consequence of the underlying acute respiratory failure or hemodynamic instability, reduced oxygen stores and increased oxygen consumption.

Moreover, the rate of difficult airway management may be higher in the intensive care unit (ICU) and in the Emergency Department (ED), prolonging the apnea time and the risk of desaturation. Finally, operator’s skills, procedures, devices and drugs, among others, may influence airway management success and patient’s outcome.

Despite the high risk of the procedure, different interventions lack high-quality evidence and we hypothesize that a heterogeneous practice among different centres and geographical areas may be
found.

The primary aim of our study is to evaluate the incidence of intubation-related adverse events in critically ill patients. Secondary aim is to evaluate current clinical practices on airway management in the in-hospital critical care setting.

Steering Committee

Vincenzo Russotto (Monza, Italy), Giacomo Bellani (Monza, Italy), Giuseppe Foti (Monza, Italy), Roberto Fumagalli (Milan, Italy), Antonio Pesenti (Milan, Italy), Paolo Pelosi (Genoa, Italy), Luigi Camporota (London), Philippe R Bauer (Rochester, USA), Konstanty Szuldrzynski (Cracow, Poland), Sheila Nainan Myatra (Mumbai, India), Jonathan Tan Jit Ern (Singapore), John Laffey ,(Ireland), Massimiliano Sorbello (Catania), Robert Greif (Bern, Switzerland), Andy Higgs (Cheshire, UK).

Administering Institution

University Hospital San Gerardo, ASST Monza, Monza, Italy

Sample Size

Collect data from at least 1000 major adverse events from airway management.

Reference

CTG1819-02
NCT03616054

Contact

David Brewster (via the ANZICS office)