Current Active Endorsed Research

A phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding.  The cryopreserved vs. liquid platelets trial

The re-evaluating the inhibition of stress erosions trial

A cluster randomised controlled trial of the clinical effectiveness and cost-effectiveness with a contemporaneous study of the ecological impact of selective decontamination of the digestive tract in critically ill patients treated in intensive care units

Treatment of invasively ventilated adults with early activity and mobilisation

​Nitric oxide on cardio pulmonary bypass in congenital heart disease

A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients

Adjunctive corticosteroid treatment in critically ill patients with septic shock

Liberal glucose control in critically Ill patient with pre-existing type 2 diabetes (LUCID): a phase II multicentre randomised controlled trial

A multicentre, prospective, observational study of the process of obtaining consent from potential participants or their substitute decision-makers in the adjunctive corticosteroid treatment in critically ill patients with septic shock (ADRENAL) Study

Pre-hospital anti-fibrinolytics for traumatic coagulopathy and haemorrhage

A multi-centre, cluster cross over, randomised registry trial comparing the safety and efficacy of proton pump inhibitors with histamine-2 receptor blockers for ulcer prophylaxis in intensive care patients

Relative hypotension and acute kidney injury in patients with shock: A prospective multicentre cohort study

Randomised evaluation of active control of temperature vs. ordinary temperature management

Short Period Incidence Study of Severe Acute Respiratory Infection

Standard versus accelerated initiation of renal replacement therapy in acute kidney injury

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT

The Plasma-Lyte 148® vs Saline study

Randomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia

​Targeted therapeutic mild hypercapnia after resuscitated cardiac arrest: A phase III multi-centre randomised controlled trial

The Augmented versus Routine approach to Giving Energy Trial

Prophylactic hypothermia to lessen traumatic brain injury

Sedation practice in intensive care evaluation randomised controlled trial

A phase 2b, multi-centre, randomised, single blinded clinical trial parallel groups comparing liberal vs. conservative oxygen therapy in mechanically ventilated adults in the Intensive Care Unit (ICU).

A survey of Australian public opinion on methods to triage intensive care patients in an influenza pandemic

Economic Evaluation of Resuscitation in Sepsis

Sedation practice in paediatric intensive care in Australia and New Zealand

Bacteraemic load and survival in septic patient

The Fluid Translation of Research into Practice Study (Fluid-TRIPS): An International Cross sectional Survey of Fluid Resuscitation Practice

Prophylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: an inception cohort study

Prophylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: A pilot randomised controlled trial

The Prophylactic hypOthermia trial to Lessen traumatic bRain injury Basal Energy Assessment Research

Restrictive versus liberal fluid therapy in major abdominal surgery

Sampling antibiotics in renal replacement therapy

The RENAL Substudy of POLAR

A multi-centre RCT of open lung strategy including permissive hypercapnia, alveolar recruitment and low airway pressures in patients with ARDS