Current Active Endorsed Research

Current Active Endorsed Research

ANZICS CTG Current Research

You can select the short title below for more information on the study.

Set up phase (4)
Study number Short name Study title
CTG 1718-06 CLIP II

A phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding.  The cryopreserved vs. liquid platelets trial


The re-evaluating the inhibition of stress erosions trial

CTG 1314-13 SuDDICU cRCT (CTG Supported Study)

A cluster randomised controlled trial of the clinical effectiveness and cost-effectiveness with a contemporaneous study of the ecological impact of selective decontamination of the digestive tract in critically ill patients treated in intensive care units

CTG 1516-05 TEAM

Treatment of invasively ventilated adults with early activity and mobilisation

Currently recruiting (15)
Study number Short name Study title
​CTG 1617-06 ​NO in CPB (Paediatric)

​Nitric oxide on cardio pulmonary bypass in congenital heart disease


A phase III randomised controlled trial of continuous beta-lactam infusion compared with intermittent beta-lactam dosing in critically ill patients


Adjunctive corticosteroid treatment in critically ill patients with septic shock

CTG 1617-04 LUCID

Liberal glucose control in critically Ill patient with pre-existing type 2 diabetes (LUCID): a phase II multicentre randomised controlled trial

​CTG 1213-03 ADRENAL Consent Substudy

A multicentre, prospective, observational study of the process of obtaining consent from potential participants or their substitute decision-makers in the adjunctive corticosteroid treatment in critically ill patients with septic shock (ADRENAL) Study

CTG 1314-05 PATCH

Pre-hospital anti-fibrinolytics for traumatic coagulopathy and haemorrhage

​CTG 1415-01 PEPTIC

A multi-centre, cluster cross over, randomised registry trial comparing the safety and efficacy of proton pump inhibitors with histamine-2 receptor blockers for ulcer prophylaxis in intensive care patients

CTG 1213-05 REACT Shock Study

Relative hypotension and acute kidney injury in patients with shock: A prospective multicentre cohort study

CTG 1617-03 The REACTOR Trial

Randomised evaluation of active control of temperature vs. ordinary temperature management

CTG 1516‐01 SPRINT‐SARI (CTG Supported Study)

Short Period Incidence Study of Severe Acute Respiratory Infection


Standard versus accelerated initiation of renal replacement therapy in acute kidney injury

​CTG 1516-03 The BALANCE Study (CTG Supported Study)

Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness: A Pilot RCT

CTG 1415-03 PLUS

The Plasma-Lyte 148® vs Saline study


Randomized, Embedded, Multifactorial Adaptive Platform trial for Community-Acquired Pneumonia

​CTG1617-001 TAME

​Targeted therapeutic mild hypercapnia after resuscitated cardiac arrest: A phase III multi-centre randomised controlled trial

Analysis & reporting (16)
Study number Short name Study title
CTG 1314-08 TARGET

The Augmented versus Routine approach to Giving Energy Trial

CTG 08-002 POLAR

Prophylactic hypothermia to lessen traumatic brain injury


Sedation practice in intensive care evaluation randomised controlled trial

​CTG 1415-04 ICU-ROX

A phase 2b, multi-centre, randomised, single blinded clinical trial parallel groups comparing liberal vs. conservative oxygen therapy in mechanically ventilated adults in the Intensive Care Unit (ICU).

CTG 1314-14 iPIT3 – The Influenza Pandemic Survey

A survey of Australian public opinion on methods to triage intensive care patients in an influenza pandemic

CTG 08-007 ARISE Economic Evaluation

Economic Evaluation of Resuscitation in Sepsis

CTG 1314-09 Baby SPICE Pilot Study

Sedation practice in paediatric intensive care in Australia and New Zealand

CTG 10-006 BLISS

Bacteraemic load and survival in septic patient

CTG 1314-10 Fluid-TRIPS

The Fluid Translation of Research into Practice Study (Fluid-TRIPS): An International Cross sectional Survey of Fluid Resuscitation Practice

CTG 1213-01 PINBALL inception cohort study

Prophylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: an inception cohort study

CTG 1415-05 PINBALL Pilot

Prophylactic intra-aortic balloon counterpulsation in high-risk cardiac surgery: A pilot randomised controlled trial


The Prophylactic hypOthermia trial to Lessen traumatic bRain injury Basal Energy Assessment Research


Restrictive versus liberal fluid therapy in major abdominal surgery

CTG 1314-04 SMARRT

Sampling antibiotics in renal replacement therapy

CTG 11-005 The RENAL Substudy of POLAR

The RENAL Substudy of POLAR


A multi-centre RCT of open lung strategy including permissive hypercapnia, alveolar recruitment and low airway pressures in patients with ARDS